Greasby nash biography of christopher

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    3. Remove traces of your submission

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    Abstract

    The kinetics and regulatory mechanisms of T cell migration through the endothelium have not been fully defined. In experimental, filter-based assays in vitro, transmigration of lymphocytes takes hours, compared with minutes, in vivo. We cultured endothelial cell (EC) monolayers on filters, solid substrates, or collagen gels and treated them with TNF-α, IFN-γ, or both prior to analysis of lymphocyte migration in the presence or absence of flow. PBL, CD4+ cells, or CD8+ cells took many hours to migrate through EC-filter constructs for all cytokine treatments. However, direct microscopic observations of EC filters, which had been mounted in a flow chamber, showed that PBL crossed the endothelial monolayer in minutes and were highly motile in the subendothelial space. Migration through EC was also observed on clear plastic, with or without flow. After a brief settling without flow, PBL and isolated CD3+ or CD4+ cells crossed EC in minutes, but the numbers of migrated cells var

  • greasby nash biography of christopher
  • Orchestral Manoeuvres in the Dark

    English band

    This article is about the grupp. For their debut skiva, see Orchestral Manoeuvres in the Dark (album).

    Orchestral Manoeuvres in the Dark (OMD) are an English electronic band formed in Meols, Merseyside in by Andy McCluskey (vocals, bass guitar) and Paul Humphreys (keyboards, vocals). Regarded as pioneers of electronic music, OMD combined an experimental, minimalist ethos with pop sensibilities, becoming key figures in the emergence of synth-pop; McCluskey and Humphreys also introduced the "synth duo" format to British popular music. In the United States, the band were an early presence in the MTV-driven Second British Invasion.

    McCluskey and Humphreys led the Id, a precursor group, from to and re-recorded their track "Electricity" as OMD's debut single in Weathering an "uncool" image and a degree of hostility from music critics, the grupp achieved popularity throughout europe with the anti-war song "Enola Gay", and gained furth